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Results: The review reveals that plant extracts with neuroprotective properties exert anti-PD effects through mechanisms including antioxidant and anti-inflammatory actions, inhibition of -synuclein (-syn) aggregation, enhancement of dopaminergic neuron survival, and restoration of synaptic function

iNap1 also promptly responds to changes in intracellular NADPH level, which significantly shortens the time and cost of the screenings

Our complementary UV-vis and fluorescence anisotropy spectroscopic analysis, together with molecular modeling, shows that the combination of the three studied mutations removes critical structural constraints at key microdomains, allowing the formation of an active-like conformation in the dark

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Because PENs such as GNPs are more resistant to extreme temperatures and can endure stomach acids, PENs can deliver CRISPR-based gene therapies through and into the GI tract